Enterovirus 71 virus-like particle vaccine: Improved production conditions for enhanced yield
Enterovirus 71 virus-like particle vaccine: Improved production conditions for enhanced yield
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Kidlington: Elsevier Ltd
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Language
English
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Kidlington: Elsevier Ltd
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Abstract To develop the enterovirus 71 (EV71) vaccine, we previously constructed a recombinant baculovirus (Bac-P1-3CD) co-expressing EV71 P1 (under polyhedrin promoter) and 3CD (under p10 promoter) proteins, which caused P1 cleavage by 3CD protease and self-assembly of virus-like particles (VLPs) in Sf-9 cells. Assuming that reducing the 3CD expre...
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Full title
Enterovirus 71 virus-like particle vaccine: Improved production conditions for enhanced yield
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TN_cdi_proquest_miscellaneous_867740495
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_867740495
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2010.08.052
