Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating
Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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CaMKII phosphorylates the GluA1 AMPA subunit at Ser831 to increase single channel conductance. Here, the authors show that coexpression of TARPs is required for phospho-Ser831 to increase conductance of GluA1/GluA2 receptors. Ser831 phosphorylation increases the efficiency with which each subunit can activate, increasing the likelihood of simultane...
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Full title
Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating
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TN_cdi_proquest_miscellaneous_868995515
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_868995515
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2804
