Direct reprogramming of fibroblasts into epiblast stem cells
Direct reprogramming of fibroblasts into epiblast stem cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The four transcription factors Oct4, Sox2, Klf4 and c-myc induce somatic cells to reprogramme to an early embryonic stem cell state. When expressed in somatic cells under culture conditions that are normally used for stem cells derived from mouse epiblast tissue of post-implantation embryos (EpiSCs), these factors drive reprogramming to a state tha...
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Full title
Direct reprogramming of fibroblasts into epiblast stem cells
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TN_cdi_proquest_miscellaneous_869570866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_869570866
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2136
