Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family...
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase
About this item
Full title
Author / Creator
Aghajan, Mariam , Jonai, Nao , Flick, Karin , Fu, Fei , Luo, Manlin , Cai, Xiaolu , Ouni, Ikram , Pierce, Nathan , Tang, Xiaobo , Lomenick, Brett , Damoiseaux, Robert , Hao, Rui , del Moral, Pierre M , Verma, Rati , Li, Ying , Li, Cheng , Houk, Kendall N , Jung, Michael E , Zheng, Ning , Huang, Lan , Deshaies, Raymond J , Kaiser, Peter and Huang, Jing
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Although general inhibitors of the ubiquitin-proteasome system have been reported, compounds targeting specific ubiquitylation enzymes should be beneficial in clinical applications and basic research. Aghajan
et al
. present an inhibitor of the yeast SCF
Met30
E3 ligase that prevents the binding of the Met30 F-box protein to the core li...
Alternative Titles
Full title
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase
Authors, Artists and Contributors
Author / Creator
Jonai, Nao
Flick, Karin
Fu, Fei
Luo, Manlin
Cai, Xiaolu
Ouni, Ikram
Pierce, Nathan
Tang, Xiaobo
Lomenick, Brett
Damoiseaux, Robert
Hao, Rui
del Moral, Pierre M
Verma, Rati
Li, Ying
Li, Cheng
Houk, Kendall N
Jung, Michael E
Zheng, Ning
Huang, Lan
Deshaies, Raymond J
Kaiser, Peter
Huang, Jing
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_874180295
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_874180295
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1645
