Matrix Metalloproteinase-Mediated Disruption of Tight Junction Proteins in Cerebral Vessels is Rever...
Matrix Metalloproteinase-Mediated Disruption of Tight Junction Proteins in Cerebral Vessels is Reversed by Synthetic Matrix Metalloproteinase Inhibitor in Focal Ischemia in Rat
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London, England: SAGE Publications
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English
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London, England: SAGE Publications
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Matrix metalloproteinases (MMPs) disrupt the blood—brain barrier (BBB) during reperfusion. Occludin and claudins are recently described tight junction proteins (TJPs) that form the BBB. We hypothesized that the opening of the BBB was because of the degradation of TJPs by the MMPs. Spontaneously hypertensive rats had a 90 mins middle cerebral artery...
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Full title
Matrix Metalloproteinase-Mediated Disruption of Tight Junction Proteins in Cerebral Vessels is Reversed by Synthetic Matrix Metalloproteinase Inhibitor in Focal Ischemia in Rat
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TN_cdi_proquest_miscellaneous_876229611
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_876229611
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ISSN
0271-678X
E-ISSN
1559-7016
DOI
10.1038/sj.jcbfm.9600375
