Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
About this item
Full title
Author / Creator
Helgason, Agnar , Pálsson, Snæbjörn , Thorleifsson, Gudmar , Grant, Struan F A , Emilsson, Valur , Gunnarsdottir, Steinunn , Adeyemo, Adebowale , Chen, Yuanxiu , Chen, Guanjie , Reynisdottir, Inga , Benediktsson, Rafn , Hinney, Anke , Hansen, Torben , Andersen, Gitte , Borch-Johnsen, Knut , Jorgensen, Torben , Schäfer, Helmut , Faruque, Mezbah , Doumatey, Ayo , Zhou, Jie , Wilensky, Robert L , Reilly, Muredach P , Rader, Daniel J , Bagger, Yu , Christiansen, Claus , Sigurdsson, Gunnar , Hebebrand, Johannes , Pedersen, Oluf , Thorsteinsdottir, Unnur , Gulcher, Jeffrey R , Kong, Augustine , Rotimi, Charles and Stefánsson, Kári
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
We recently described an association between risk of type 2diabetes and variants in the transcription factor 7-like 2 gene (
TCF7L2
; formerly
TCF4
), with a population attributable risk (PAR) of 17%–28% in three populations of European ancestry
1
. Here, we refine the definition of the
TCF7L2
type 2diabetes risk variant, Ha...
Alternative Titles
Full title
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
Authors, Artists and Contributors
Author / Creator
Pálsson, Snæbjörn
Thorleifsson, Gudmar
Grant, Struan F A
Emilsson, Valur
Gunnarsdottir, Steinunn
Adeyemo, Adebowale
Chen, Yuanxiu
Chen, Guanjie
Reynisdottir, Inga
Benediktsson, Rafn
Hinney, Anke
Hansen, Torben
Andersen, Gitte
Borch-Johnsen, Knut
Jorgensen, Torben
Schäfer, Helmut
Faruque, Mezbah
Doumatey, Ayo
Zhou, Jie
Wilensky, Robert L
Reilly, Muredach P
Rader, Daniel J
Bagger, Yu
Christiansen, Claus
Sigurdsson, Gunnar
Hebebrand, Johannes
Pedersen, Oluf
Thorsteinsdottir, Unnur
Gulcher, Jeffrey R
Kong, Augustine
Rotimi, Charles
Stefánsson, Kári
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_877601274
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_877601274
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng1960
