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Complexin cross-links prefusion SNAREs into a zigzag array

Complexin cross-links prefusion SNAREs into a zigzag array

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_881087546

Complexin cross-links prefusion SNAREs into a zigzag array

About this item

Full title

Complexin cross-links prefusion SNAREs into a zigzag array

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2011-08, Vol.18 (8), p.927-933

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Structural studies of complexin bound to a mimetic of a prefusion SNARE complex provide insight into how complexin 'clamps' SNARE complex assembly, thereby inhibiting membrane fusion. While the central helix of complexin is anchored to a SNARE complex, its accessory helix extends away and bridges to a second SNARE complex, generating a zigzag array...

Alternative Titles

Full title

Complexin cross-links prefusion SNAREs into a zigzag array

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_881087546

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_881087546

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.2101

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