Autoantigen discovery with a synthetic human peptidome
Autoantigen discovery with a synthetic human peptidome
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Larman
et al
. create a phage library containing >400,000 sequences encoding peptides that cover all open reading frames in the human genome. They then use this synthetic peptidome to discover novel autoantigens targeted by antibodies in the cerebrospinal fluid of individuals with a neurological autoimmune disease.
Immune responses targeti...
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Full title
Autoantigen discovery with a synthetic human peptidome
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TN_cdi_proquest_miscellaneous_883048992
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_883048992
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1856
