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Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monoph...

Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monoph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_896522961

Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monophosphate-dependent and Ras-proximate protein-dependent inactivation of extracellular regulated kinase

About this item

Full title

Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monophosphate-dependent and Ras-proximate protein-dependent inactivation of extracellular regulated kinase

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2011-10, Vol.45 (4), p.692-703

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

Fibrocytes comprise a recently described cell type of blood-derived, fibroblast-like cells that are recruited from the circulation to sites of wound repair, vascular remodeling, or fibrotic tissue remodeling. We recently showed that the stable prostacyclin analogue treprostinil, a clinically approved drug for pulmonary arterial hypertension (PAH),...

Alternative Titles

Full title

Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monophosphate-dependent and Ras-proximate protein-dependent inactivation of extracellular regulated kinase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_896522961

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_896522961

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/rcmb.2010-0240OC

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