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The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_902675037

The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

About this item

Full title

The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2011-11, Vol.18 (11), p.1290-1296

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The mitochondrial transcription factor Tfam has a role in organizing the mitochondrial genome, in addition to its transcriptional function. Structural studies of human Tfam in complex with a mitochondrial DNA promoter show that Tfam imposes a U-turn on the DNA similarly to the unrelated HU family of proteins, which play analogous architectural role...

Alternative Titles

Full title

The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_902675037

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_902675037

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.2159

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