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Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of...

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904481649

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes

About this item

Full title

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2011-06, Vol.18 (6), p.708-714

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Identifying genes associated with SNPs in non-coding regions is difficult as the SNPs are often located far from the promoters they impact. Cross-species comparison of sites occupied by the insulating protein CTCF reveals conserved boundaries between genes often associated with disease. Multiple sclerosis–associated SNPs occur in the
GFI1-EVI5

Alternative Titles

Full title

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_904481649

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904481649

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.2059

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