Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion
Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion
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Author / Creator
Atarashi, Ryuichiro , Satoh, Katsuya , Sano, Kazunori , Fuse, Takayuki , Yamaguchi, Naohiro , Ishibashi, Daisuke , Matsubara, Takehiro , Nakagaki, Takehiro , Yamanaka, Hitoki , Shirabe, Susumu , Yamada, Masahito , Mizusawa, Hidehiro , Kitamoto, Tetsuyuki , Klug, Genevieve , McGlade, Amelia , Collins, Steven J and Nishida, Noriyuki
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Definitive diagnosis of prion disease currently requires postmortem brain tissue. Now, Ryuichiro Atarashi and colleagues have discovered an assay that can identify prions in human cerebrospinal fluid. This assay could allow for diagnosis of disease in living humans.
The development of technologies for the
in vitro
amplification of abnormal...
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Full title
Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion
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Record Identifier
TN_cdi_proquest_miscellaneous_907153934
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907153934
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2294
