Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuro...
Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Neuromyelitis optica (NMO) is an inflammatory disease affecting the optic nerve and spinal cord, in which autoantibodies against aquaporin 4 (AQP4) water channel protein probably play a pathogenic role. Here we show that a B-cell subpopulation, exhibiting the CD19intCD27highCD38highCD180⁻ phenotype, is selectively increased in the peripheral blood...
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Full title
Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
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TN_cdi_proquest_miscellaneous_907156710
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907156710
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1017385108
