Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration
Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Regeneration requires initiation of programs tailored to the identity of missing parts. Head-versus-tail regeneration in planarians presents a paradigm for study of this phenomenon. After injury, Wnt signaling promotes tail regeneration. We report that wounding elicits expression of the Wnt inhibitor notum preferentially at anterior-facing wounds....
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Full title
Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration
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TN_cdi_proquest_miscellaneous_907934408
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907934408
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1202143