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Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907934408

Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

About this item

Full title

Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2011-05, Vol.332 (6031), p.852-855

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Regeneration requires initiation of programs tailored to the identity of missing parts. Head-versus-tail regeneration in planarians presents a paradigm for study of this phenomenon. After injury, Wnt signaling promotes tail regeneration. We report that wounding elicits expression of the Wnt inhibitor notum preferentially at anterior-facing wounds....

Alternative Titles

Full title

Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_907934408

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907934408

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1202143

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