Enforced viral replication activates adaptive immunity and is essential for the control of a cytopat...
Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus
About this item
Full title
Author / Creator
Honke, Nadine , Shaabani, Namir , Cadeddu, Giuseppe , Sorg, Ursula R , Zhang, Dong-Er , Trilling, Mirko , Klingel, Karin , Sauter, Martina , Kandolf, Reinhard , Gailus, Nicole , van Rooijen, Nico , Burkart, Christoph , Baldus, Stephan E , Grusdat, Melanie , Löhning, Max , Hengel, Hartmut , Pfeffer, Klaus , Tanaka, Masato , Häussinger, Dieter , Recher, Mike , Lang, Philipp A and Lang, Karl S
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Type 1 interferon limits virus replication. Lang and colleagues show that expression of Usp18 in metallophilic macrophages results in less interferon responsiveness, which allows locally restricted virus replication and the induction of adaptive immune responses.
The innate immune system limits viral replication via type I interferon and also in...
Alternative Titles
Full title
Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus
Authors, Artists and Contributors
Author / Creator
Shaabani, Namir
Cadeddu, Giuseppe
Sorg, Ursula R
Zhang, Dong-Er
Trilling, Mirko
Klingel, Karin
Sauter, Martina
Kandolf, Reinhard
Gailus, Nicole
van Rooijen, Nico
Burkart, Christoph
Baldus, Stephan E
Grusdat, Melanie
Löhning, Max
Hengel, Hartmut
Pfeffer, Klaus
Tanaka, Masato
Häussinger, Dieter
Recher, Mike
Lang, Philipp A
Lang, Karl S
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_912106351
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_912106351
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2169
