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ArticlesPeer ReviewedFull Text
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions
Author / Creator:Bakowski, Malina A. ; Beutler, Nathan ; Wolff, Karen C. ; Kirkpatrick, Melanie G. ; Chen, Emily ; Nguyen, Tu-Trinh H. ; Riva, Laura ; Shaabani, Namir ; Parren, Mara ; Ricketts, James ; Gupta, Anil K. ; Pan, Kastin ; Kuo, Peiting ; Fuller, MacKenzie ; Garcia, Elijah ; Teijaro, John R. ; Yang, Linlin ; Sahoo, Debashis ; Chi, Victor ; Huang, Edward ; Vargas, Natalia ; Roberts, Amanda J. ; Das, Soumita ; Ghosh, Pradipta ; Woods, Ashley K. ; Joseph, Sean B. ; Hull, Mitchell V. ; Schultz, Peter G. ; Burton, Dennis R. ; Chatterjee, Arnab K. ; McNamara, Case W. ; Rogers, Thomas F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-06, Vol.12 (1), p.3309-3309, Article 3309
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Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells
Author / Creator:Honke, Nadine ; Lowin, Torsten ; Opgenoorth, Birgit ; Shaabani, Namir ; Lautwein, Alexander ; Teijaro, John R. ; Schneider, Matthias ; Pongratz, Georg
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2022-01, Vol.20 (1), p.e3001513-e3001513
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Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity
Author / Creator:Lang, Philipp A ; Lang, Karl S ; Xu, Haifeng C ; Grusdat, Melanie ; Parish, Ian A ; Recher, Mike ; Elford, Alisha R ; Dhanji, Salim ; Shaabani, Namir ; Tran, Charles W ; Dissanayake, Dilan ; Rahbar, Ramtin ; Ghazarian, Magar ; Brüstle, Anne ; Fine, Jason ; Chen, Peter ; Weaver, Casey T ; Klose, Christoph ; Diefenbach, Andreas ; Häussinger, Dieter ; Carlyle, James R ; Kaech, Susan M ; Mak, Tak W ; Ohashi, Pamela S
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (4), p.1210-1215
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Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus
Author / Creator:Honke, Nadine ; Shaabani, Namir ; Cadeddu, Giuseppe ; Sorg, Ursula R ; Zhang, Dong-Er ; Trilling, Mirko ; Klingel, Karin ; Sauter, Martina ; Kandolf, Reinhard ; Gailus, Nicole ; van Rooijen, Nico ; Burkart, Christoph ; Baldus, Stephan E ; Grusdat, Melanie ; Löhning, Max ; Hengel, Hartmut ; Pfeffer, Klaus ; Tanaka, Masato ; Häussinger, Dieter ; Recher, Mike ; Lang, Philipp A ; Lang, Karl S
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2012-01, Vol.13 (1), p.51-57
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CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection
Author / Creator:Shaabani, Namir ; Duhan, Vikas ; Khairnar, Vishal ; Gassa, Asmae ; Ferrer-Tur, Rita ; Häussinger, Dieter ; Recher, Mike ; Zelinskyy, Gennadiy ; Liu, Jia ; Dittmer, Ulf ; Trilling, Mirko ; Scheu, Stefanie ; Hardt, Cornelia ; Lang, Philipp A ; Honke, Nadine ; Lang, Karl S
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2016-11, Vol.7 (11), p.e2446-e2446
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Evaluation of SARS-CoV‑2 Main Protease Inhibitors Using a Novel Cell-Based Assay
Author / Creator:Cao, Wenyue ; Cho, Chia-Chuan Dean ; Geng, Zhi Zachary ; Shaabani, Namir ; Ma, Xinyu R ; Vatansever, Erol C ; Alugubelli, Yugendar R ; Ma, Yuying ; Chaki, Sankar P ; Ellenburg, William H ; Yang, Kai S ; Qiao, Yuchen ; Allen, Robert ; Neuman, Benjamin W ; Ji, Henry ; Xu, Shiqing ; Liu, Wenshe Ray
Publisher:United States: American Chemical Society
Journal title:ACS central science, 2022-02, Vol.8 (2), p.192-204
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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology
Author / Creator:David, Paul ; Drabczyk-Pluta, Malgorzata ; Pastille, Eva ; Knuschke, Torben ; Werner, Tanja ; Honke, Nadine ; Megger, Dominik A. ; Akhmetzyanova, Ilseyar ; Shaabani, Namir ; Eyking-Singer, Annette ; Cario, Elke ; Kershaw, Olivia ; Gruber, Achim D. ; Tenbusch, Matthias ; Dietze, Kirsten K. ; Trilling, Mirko ; Liu, Jia ; Schadendorf, Dirk ; Streeck, Hendrik ; Lang, Karl S. ; Xie, Youhua ; Zimmer, Lisa ; Sitek, Barbara ; Paschen, Annette ; Westendorf, Astrid M. ; Dittmer, Ulf ; Zelinskyy, Gennadiy
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-03, Vol.16 (3), p.e1008340-e1008340
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ArticlesPeer ReviewedFull Text
Usp18 Driven Enforced Viral Replication in Dendritic Cells Contributes to Break of Immunological Tolerance in Autoimmune Diabetes
Author / Creator:Honke, Nadine ; Shaabani, Namir ; Zhang, Dong-Er ; Iliakis, George ; Xu, Haifeng C. ; Häussinger, Dieter ; Recher, Mike ; Löhning, Max ; Lang, Philipp A. ; Lang, Karl S.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2013-10, Vol.9 (10), p.e1003650
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ArticlesPeer ReviewedFull Text
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
Author / Creator:Khairnar, Vishal ; Duhan, Vikas ; Maney, Sathish Kumar ; Honke, Nadine ; Shaabani, Namir ; Pandyra, Aleksandra A. ; Seifert, Marc ; Pozdeev, Vitaly ; Xu, Haifeng C. ; Sharma, Piyush ; Baldin, Fabian ; Marquardsen, Florian ; Merches, Katja ; Lang, Elisabeth ; Kirschning, Carsten ; Westendorf, Astrid M. ; Häussinger, Dieter ; Lang, Florian ; Dittmer, Ulf ; Küppers, Ralf ; Recher, Mike ; Hardt, Cornelia ; Scheffrahn, Inka ; Beauchemin, Nicole ; Göthert, Joachim R. ; Singer, Bernhard B. ; Lang, Philipp A. ; Lang, Karl S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-02, Vol.6 (1), p.6217-6217, Article 6217
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ArticlesPeer ReviewedFull Text
Involvement of Toso in activation of monocytes, macrophages, and granulocytes
Author / Creator:Lang, Karl S. ; Lang, Philipp A. ; Meryk, Andreas ; Pandyra, Aleksandra A. ; Boucher, Louis-Martin ; Pozdeev, Vitaly I. ; Tusche, Michael W. ; Göthert, Joachim R. ; Haight, Julian ; Wakeham, Andrew ; You-Ten, Annick J. ; MclIwain, David R. ; Merches, Katja ; Khairnar, Vishal ; Recher, Mike ; Nolan, Garry P. ; Hitoshi, Yasumichi ; Funkner, Pauline ; Navarini, Alexander A. ; Verschoor, Admar ; Shaabani, Namir ; Honke, Nadine ; Penn, Linda Z. ; Ohashi, Pamela S. ; Häussinger, Dieter ; Lee, Kyeong-Hee ; Mak, Tak W.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (7), p.2593-2598
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ArticlesPeer ReviewedFull Text
Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection
Author / Creator:Honke, Nadine ; Shaabani, Namir ; Hardt, Cornelia ; Krings, Caroline ; Häussinger, Dieter ; Lang, Philipp A. ; Lang, Karl S. ; Keitel, Verena
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Cellular physiology and biochemistry, 2017-01, Vol.41 (1), p.323-338
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IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts
Author / Creator:Gassa, Asmae ; Jian, Fu ; Kalkavan, Halime ; Duhan, Vikas ; Honke, Nadine ; Shaabani, Namir ; Friedrich, Sarah-Kim ; Dolff, Sebastian ; Wahlers, Thorsten ; Kribben, Andreas ; Hardt, Cornelia ; Lang, Philipp A. ; Witzke, Oliver ; Lang, Karl S.
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2016-01, Vol.38 (3), p.1171-1181
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Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection
Author / Creator:Merches, Katja ; Khairnar, Vishal ; Knuschke, Torben ; Shaabani, Namir ; Honke, Nadine ; Duhan, Vikas ; Recher, Mike ; Navarini, Alexander A. ; Hardt, Cornelia ; Häussinger, Dieter ; Tümmler, Burkhard ; Gulbins, Erich ; Futerman, Anthony H. ; Hoffmann, Daniel ; Lang, Florian ; Lang, Philipp A. ; Westendorf, Astrid M. ; Lang, Karl S.
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2015-08, Vol.36 (6), p.2379-2392
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High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model
Author / Creator:Gassa, Asmae ; Kalkavan, Halime ; Jian, Fu ; Duhan, Vikas ; Khairnar, Vishal ; Shaabani, Namir ; Honke, Nadine ; Carpinteiro, Alexander ; Botezatu, Lacramioara ; Crivello, Pietro ; Dolff, Sebastian ; Ferencik, Stanislav ; Häussinger, Dieter ; Khandanpour, Cyrus ; Fleischhauer, Katharina ; Witzke, Oliver ; Wahlers, Thorsten ; Hardt, Cornelia ; Lang, Philipp A. ; Lang, Karl S.
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2016-01, Vol.38 (4), p.1343-1353
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HYBRiD: hydrogel-reinforced DISCO for clearing mammalian bodies
Author / Creator:Nudell, Victoria ; Wang, Yu ; Pang, Zhengyuan ; Lal, Neeraj K. ; Huang, Min ; Shaabani, Namir ; Kanim, Wesam ; Teijaro, John ; Maximov, Anton ; Ye, Li
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2022-04, Vol.19 (4), p.479-485
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ArticlesPeer ReviewedFull Text
Multiple functions of USP18
Author / Creator:Honke, Nadine ; Shaabani, Namir ; Zhang, Dong-Er ; Hardt, Cornelia ; Lang, Karl S
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2016-11, Vol.7 (11), p.e2444-e2444
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Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells
Author / Creator:Nadine Honke ; Torsten Lowin ; Birgit Opgenoorth ; Namir Shaabani ; Alexander Lautwein ; John R. Teijaro ; Matthias Schneider ; Georg Pongratz
Publisher:Public Library of Science (PLoS)
Journal title:PLoS biology, 2022-01, Vol.20 (1)
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Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection
Author / Creator:Oh, Chang-ki ; Nakamura, Tomohiro ; Beutler, Nathan ; Zhang, Xu ; Piña-Crespo, Juan ; Talantova, Maria ; Ghatak, Swagata ; Trudler, Dorit ; Carnevale, Lauren N. ; McKercher, Scott R. ; Bakowski, Malina A. ; Diedrich, Jolene K. ; Roberts, Amanda J. ; Woods, Ashley K. ; Chi, Victor ; Gupta, Anil K. ; Rosenfeld, Mia A. ; Kearns, Fiona L. ; Casalino, Lorenzo ; Shaabani, Namir ; Liu, Hejun ; Wilson, Ian A. ; Amaro, Rommie E. ; Burton, Dennis R. ; Yates, John R. ; Becker, Cyrus ; Rogers, Thomas F. ; Chatterjee, Arnab K. ; Lipton, Stuart A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2023-03, Vol.19 (3), p.275-283
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Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8+ T-cell priming and viral control
Author / Creator:Duhan, Vikas ; Khairnar, Vishal ; Friedrich, Sarah-Kim ; Zhou, Fan ; Gassa, Asmae ; Honke, Nadine ; Shaabani, Namir ; Gailus, Nicole ; Botezatu, Lacramioara ; Khandanpour, Cyrus ; Dittmer, Ulf ; Häussinger, Dieter ; Recher, Mike ; Hardt, Cornelia ; Lang, Philipp A. ; Lang, Karl S.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-01, Vol.6 (1), p.19191-19191, Article 19191
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CD169 super(+) macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection
Author / Creator:Shaabani, Namir ; Duhan, Vikas ; Khairnar, Vishal ; Gassa, Asmae ; Ferrer-Tur, Rita ; Haeussinger, Dieter ; Recher, Mike ; Zelinskyy, Gennadiy ; Liu, Jia ; Dittmer, Ulf ; Trilling, Mirko ; Scheu, Stefanie ; Hardt, Cornelia ; Lang, Philipp A ; Honke, Nadine ; Lang, Karl S
Journal title:Cell death & disease, 2016-11, Vol.7 (11), p.e2446-e2446
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Showing 1 to 20 of 32 results

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Drug repurposing screens identify chemical entities for the development of COVID-19 interventions

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Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells

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Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

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Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

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CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection

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Evaluation of SARS-CoV‑2 Main Protease Inhibitors Using a Novel Cell-Based Assay

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Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology

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Usp18 Driven Enforced Viral Replication in Dendritic Cells Contributes to Break of Immunological Tolerance in Autoimmune Diabetes

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CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production

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Involvement of Toso in activation of monocytes, macrophages, and granulocytes

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Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection

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IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts

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Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection

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High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model

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HYBRiD: hydrogel-reinforced DISCO for clearing mammalian bodies

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Multiple functions of USP18

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Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells

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Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection

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Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8+ T-cell priming and viral control

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CD169 super(+) macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection

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