The unfolded protein response: controlling cell fate decisions under ER stress and beyond
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Alterations in the function of the endoplasmic reticulum (ER) can result in the accumulation of unfolded or misfolded proteins, a cellular condition referred to as ER stress. ER stress engages the unfolded protein response (UPR), an adaptive reaction that reduces unfolded protein load to maintain cell viability and function.
Condit...
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Full title
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
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TN_cdi_proquest_miscellaneous_917577232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_917577232
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ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm3270
