Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Resistance to the antibiotic fusidic acid (FA) in the human pathogen Staphylococcus aureus usually results from expression of FusB-type proteins (FusB or FusC). These proteins bind to elongation factor G (EF-G), the target of FA, and rescue translation from FA-mediated inhibition by an unknown mechanism. Here we show that the FusB family are two-do...
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Full title
Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid
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TN_cdi_proquest_miscellaneous_921141218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_921141218
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1117275109
