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BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus

BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_928905392

BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus

About this item

Full title

BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus

Publisher

United States: Nature Publishing Group

Journal title

Immunology and cell biology, 2012-03, Vol.90 (3), p.293-303

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

More information

Scope and Contents

Contents

Recently, the B cell has emerged as a cornerstone of systemic lupus erythematosus (SLE) pathogenesis. This has been highlighted by studies of the cytokine B‐cell‐activating factor of the tumour necrosis factor (TNF) family (BAFF), a crucial factor regulating B‐cell maturation, survival and function. Overexpression of BAFF in mice leads to the devel...

Alternative Titles

Full title

BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_928905392

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_928905392

Other Identifiers

ISSN

0818-9641

E-ISSN

1440-1711

DOI

10.1038/icb.2011.111

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