Functions of the APP gene family in the nervous system: insights from mouse models
Functions of the APP gene family in the nervous system: insights from mouse models
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Language
English
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Contents
The amyloid precursor protein (APP) plays a key role in the pathogenesis of Alzheimer’s disease (AD), as proteolytical cleavage of APP gives rise to the β-amyloid peptide which is deposited in the brains of Alzheimer patients. During the past years, intense research efforts have been directed at elucidating the physiological function(s) of APP and...
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Full title
Functions of the APP gene family in the nervous system: insights from mouse models
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TN_cdi_proquest_miscellaneous_929505764
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_929505764
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ISSN
0014-4819
E-ISSN
1432-1106
DOI
10.1007/s00221-011-2861-2
