Role of RANK Ligand and Denosumab, a Targeted RANK Ligand Inhibitor, in Bone Health and Osteoporosis...
Role of RANK Ligand and Denosumab, a Targeted RANK Ligand Inhibitor, in Bone Health and Osteoporosis: A Review of Preclinical and Clinical Data
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United States: EM Inc USA
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English
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United States: EM Inc USA
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AbstractBackgroundPostmenopausal osteoporosis results from bone loss and decreased bone strength mediated by an increased rate of bone remodeling secondary to reduced estrogen levels. Remodeling cycles are initiated by osteoclasts, the formation, function, and survival of which depend on RANK ligand (RANKL). RANKL inhibition therefore represents a...
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Role of RANK Ligand and Denosumab, a Targeted RANK Ligand Inhibitor, in Bone Health and Osteoporosis: A Review of Preclinical and Clinical Data
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TN_cdi_proquest_miscellaneous_948893253
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_948893253
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ISSN
0149-2918
E-ISSN
1879-114X
DOI
10.1016/j.clinthera.2012.02.002
