Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferonβ...
Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferonβ therapy in multiple sclerosis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Interferon-
β
(IFN
β
) therapy is effective in approximately half of the patients with relapsing-remitting multiple sclerosis (RRMS). Clinical non-responders were characterized by an increased expression of IFN response genes before the start of therapy, and a lack of a pharmacologically induced increase in IFN response gene activity. B...
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Full title
Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferonβ therapy in multiple sclerosis
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TN_cdi_proquest_miscellaneous_968168527
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_968168527
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ISSN
1466-4879
E-ISSN
1476-5470
DOI
10.1038/gene.2011.18
