Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients...
Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Recombinant adeno-associated virus (rAAV) is a promising gene delivery vector and has recently been used in patients with hemophilia. One limitation of AAV application is that most humans have experienced wild-type AAV serotype 2 exposure, which frequently generates neutralizing antibodies (NAbs) that may inhibit rAAV2 vector transduction. Employin...
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Full title
Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia
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TN_cdi_proquest_miscellaneous_968174731
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_968174731
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ISSN
0969-7128
E-ISSN
1476-5462
DOI
10.1038/gt.2011.90
