Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice
Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice
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United States: National Academy of Sciences of the United States of America
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Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
TALL-1/Blys/BAFF is a member of the tumor necrosis factor (TNF) ligand superfamily that is functionally involved in B cell proliferation. Here, we describe B cell hyperplasia and autoimmune lupus-like changes in transgenic mice expressing TALL-1 under the control of a β -actin promoter. The TALL-1 transgenic mice showed severe enlargement of spleen...
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Full title
Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice
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TN_cdi_pubmed_primary_10716715
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10716715
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.97.7.3370