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Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice

Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10716715

Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice

About this item

Full title

Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-03, Vol.97 (7), p.3370-3375

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

TALL-1/Blys/BAFF is a member of the tumor necrosis factor (TNF) ligand superfamily that is functionally involved in B cell proliferation. Here, we describe B cell hyperplasia and autoimmune lupus-like changes in transgenic mice expressing TALL-1 under the control of a β -actin promoter. The TALL-1 transgenic mice showed severe enlargement of spleen...

Alternative Titles

Full title

Severe B Cell Hyperplasia and Autoimmune Disease in TALL-1 Transgenic Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_10716715

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10716715

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.97.7.3370

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