Survival Motor Neuron Protein Modulates Neuron-Specific Apoptosis
Survival Motor Neuron Protein Modulates Neuron-Specific Apoptosis
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences of the United States of America
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Scope and Contents
Contents
Spinal muscular atrophy (SMA) is attributed to mutations in the SMN1 gene, leading to loss of spinal cord motor neurons. The neurotropic Sindbis virus vector system was used to investigate a role for the survival motor neuron (SMN) protein in regulating neuronal apoptosis. Here we show that SMN protects primary neurons and differentiated neuron-lik...
Alternative Titles
Full title
Survival Motor Neuron Protein Modulates Neuron-Specific Apoptosis
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_11078511
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_11078511
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.230364197
