Expanding Expression of the 5-Lipoxygenase Pathway within the Arterial Wall during Human Atherogenes...
Expanding Expression of the 5-Lipoxygenase Pathway within the Arterial Wall during Human Atherogenesis
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Author / Creator
Spanbroek, Rainer , Gräbner, Rolf , Lötzer, Katharina , Hildner, Markus , Urbach, Anja , Rühling, Katharina , Michael P. W. Moos , Kaiser, Brigitte , Cohnert, Tina U. , Wahlers, Thorsten , Zieske, Arthur , Plenz, Gabriele , Robenek, Horst , Salbach, Peter , Kühn, Hartmut , Rådmark, Olof , Samuelsson, Bengt and Andreas J. R. Habenicht
Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Oxidation products of low-density lipoproteins have been suggested to promote inflammation during atherogenesis, and reticulocyte-type 15-lipoxygenase has been implicated to mediate this oxidation. In addition, the 5-lipoxygenase cascade leads to formation of leukotrienes, which exhibit strong proinflammatory activities in cardiovascular tissues. H...
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Full title
Expanding Expression of the 5-Lipoxygenase Pathway within the Arterial Wall during Human Atherogenesis
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Record Identifier
TN_cdi_pubmed_primary_12552108
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12552108
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.242716099
