Germinal Center-Associated Nuclear Protein Contributes to Affinity Maturation of B Cell Antigen Rece...
Germinal Center-Associated Nuclear Protein Contributes to Affinity Maturation of B Cell Antigen Receptor in T Cell-Dependent Responses
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Acquired immunity depends on proliferation and differentiation of antigen (Ag)-specific B cells in germinal centers (GCs) of lymphoid follicles in response to T cell-dependent Ags. Here, we studied the function of GC-associated nuclear protein that is selectively upregulated in GC-B cells. B cell-specific ganp-deficient mice were compromised in aff...
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Full title
Germinal Center-Associated Nuclear Protein Contributes to Affinity Maturation of B Cell Antigen Receptor in T Cell-Dependent Responses
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TN_cdi_pubmed_primary_14715907
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_14715907
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0307609100
