Acute Myeloid Leukemia with Complex Karyotypes and Abnormal Chromosome 21: Amplification Discloses O...
Acute Myeloid Leukemia with Complex Karyotypes and Abnormal Chromosome 21: Amplification Discloses Overexpression of APP, ETS2, and ERG Genes
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Molecular mechanisms of leukemogenesis have been successfully unraveled by studying genes involved in simple rearrangements including balanced translocations and inversions. In contrast, little is known about genes altered in complex karyotypic abnormalities. We studied acute myeloid leukemia (AML) patients with complex karyotypes and abnormal chro...
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Full title
Acute Myeloid Leukemia with Complex Karyotypes and Abnormal Chromosome 21: Amplification Discloses Overexpression of APP, ETS2, and ERG Genes
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TN_cdi_pubmed_primary_15007164
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_15007164
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0400272101