Alternative Inclusion of Fibroblast Growth Factor Receptor 2 Exon IIIc in Dunning Prostate Tumors Re...
Alternative Inclusion of Fibroblast Growth Factor Receptor 2 Exon IIIc in Dunning Prostate Tumors Reveals Unexpected Epithelial Mesenchymal Plasticity
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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In epithelial cells, alternative splicing of fibroblast growth factor receptor 2 (FGFR2) transcripts leads to the expression of the FGFR2(IIIb) isoform, whereas in mesenchymal cells, the same process results in the synthesis of FGFR2(IIIc). Expression of the FGFR2(IIIc) isoform during prostate tumor progression suggests a disruption of the epitheli...
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Full title
Alternative Inclusion of Fibroblast Growth Factor Receptor 2 Exon IIIc in Dunning Prostate Tumors Reveals Unexpected Epithelial Mesenchymal Plasticity
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TN_cdi_pubmed_primary_16963563
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_16963563
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0603090103
