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Multipotent Stromal Cells from Human Marrow Home to and Promote Repair of Pancreatic Islets and Rena...

Multipotent Stromal Cells from Human Marrow Home to and Promote Repair of Pancreatic Islets and Rena...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_17088535

Multipotent Stromal Cells from Human Marrow Home to and Promote Repair of Pancreatic Islets and Renal Glomeruli in Diabetic NOD/scid Mice

About this item

Full title

Multipotent Stromal Cells from Human Marrow Home to and Promote Repair of Pancreatic Islets and Renal Glomeruli in Diabetic NOD/scid Mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (46), p.17438-17443

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

We tested the hypothesis that multipotent stromal cells from human bone marrow (hMSCs) can provide a potential therapy for human diabetes mellitus. Severe but nonlethal hyperglycemia was produced in NOD/scid mice with daily low doses of streptozotocin on days 1-4, and hMSCs were delivered via intracardiac infusion on days 10 and 17. The hMSCs lower...

Alternative Titles

Full title

Multipotent Stromal Cells from Human Marrow Home to and Promote Repair of Pancreatic Islets and Renal Glomeruli in Diabetic NOD/scid Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_17088535

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_17088535

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0608249103

How to access this item