Human lupus autoantibodies against NMDA receptors mediate cognitive impairment
Human lupus autoantibodies against NMDA receptors mediate cognitive impairment
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Neuropsychiatric systemic lupus erythematosus, which often entails cognitive disturbances and memory loss, has become a major complication for lupus patients. Previously, we developed a murine model of neuropsychiatric lupus based on Abs that cross-react with dsDNA and the NMDA receptor (NMDAR). We showed that these murine Abs impair cognition when...
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Full title
Human lupus autoantibodies against NMDA receptors mediate cognitive impairment
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TN_cdi_pubmed_primary_17170137
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_17170137
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0608397104
