Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2
Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Increased intestinal permeability (IP) has emerged recently as a common underlying mechanism in the pathogenesis of allergic, inflammatory, and autoimmune diseases. The characterization of zonulin, the only physiological mediator known to regulate IP reversibly, has remained elusive. Through proteomic analysis of human sera, we have now identified...
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Full title
Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2
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TN_cdi_pubmed_primary_19805376
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19805376
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0906773106
