Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Contents
Extracellular adenosine is a potent immunosuppressor that accumulates during tumor growth. We performed proof-of-concept studies investigating the therapeutic potential and mechanism of action of monoclonal antibody (mAb)-based therapy against CD73, an ecto-enzyme overexpressed on breast-cancer cells that catalyzes the dephosphorylation of adenosin...
Alternative Titles
Full title
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
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Record Identifier
TN_cdi_pubmed_primary_20080644
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20080644
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0908801107
