Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate an...
Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon
About this item
Full title
Author / Creator
Peyrin-Biroulet, Laurent , Beisner, Julia , Wang, Guoxing , Nuding, Sabine , Oommen, Sajit Thottathil , Kelly, Denise , Parmentier-Decrucq, Erika , Dessein, Rodrigue , Merour, Emilie , Chavatte, Philipe , Grandjean, Teddy , Bressenot, Aude , Desreumaux, Pierre , Colombel, Jean-Frédéric , Desvergne, Béatrice , Stange, Eduard F , Wehkamp, Jan and Chamaillard, Mathias
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Crohn's disease (CD), a major form of human inflammatory bowel disease, is characterized by primary immunodeficiencies. The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is essential for intestinal homeostasis in response to both dietary- and microbiota-derived signals. Its role in host defense remains unknown, however....
Alternative Titles
Full title
Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon
Authors, Artists and Contributors
Author / Creator
Beisner, Julia
Wang, Guoxing
Nuding, Sabine
Oommen, Sajit Thottathil
Kelly, Denise
Parmentier-Decrucq, Erika
Dessein, Rodrigue
Merour, Emilie
Chavatte, Philipe
Grandjean, Teddy
Bressenot, Aude
Desreumaux, Pierre
Colombel, Jean-Frédéric
Desvergne, Béatrice
Stange, Eduard F
Wehkamp, Jan
Chamaillard, Mathias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_20421464
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20421464
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0905745107
