critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage...
critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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More information
Scope and Contents
Contents
During infection, vertebrates develop "sickness syndrome," characterized by fever, anorexia, behavioral withdrawal, acute-phase protein responses, and inflammation. These pathophysiological responses are mediated by cytokines, including TNF and IL-1, released during the innate immune response to invasion. Even in the absence of infection, qualitati...
Alternative Titles
Full title
critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
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Record Identifier
TN_cdi_pubmed_primary_20547845
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20547845
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1003893107
