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Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammat...

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20643923

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

About this item

Full title

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (31), p.13724-13729

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Previous reports suggested that culture as 3D aggregates or as spheroids can increase the therapeutic potential of the adult stem/progenitor cells referred to as mesenchymal stem cells or multipotent mesenchymal stromal cells (MSCs). Here we used a hanging drop protocol to prepare human MSCs (hMSCs) as spheroids that maximally expressed TNFα stimul...

Alternative Titles

Full title

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_20643923

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20643923

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1008117107

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