Glucocorticoid enhances hypoxia- and/or transforming growth factor-β-induced plasminogen activator i...
Glucocorticoid enhances hypoxia- and/or transforming growth factor-β-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells
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Publisher
Japan: Springer Japan
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Language
English
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Publisher
Japan: Springer Japan
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Background
Glucocorticoid (GC) treatment reportedly exaggerates renal fibrosis in progressive kidney diseases during which hypoxia occurs as an unavoidable consequence in renal tubular cells. Two major fibrotic factors, hypoxia and transforming growth factor-β (TGF-β), upregulate the production of plasminogen activator inhibitor-1 (PAI-1), a fib...
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Full title
Glucocorticoid enhances hypoxia- and/or transforming growth factor-β-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells
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Record Identifier
TN_cdi_pubmed_primary_21042829
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21042829
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ISSN
1342-1751
E-ISSN
1437-7799
DOI
10.1007/s10157-010-0351-7
