Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglycerid...
Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Fatty acids (FAs) are essential for cell survival, yet their overaccumulation causes lipotoxicity. To prevent lipotoxicity, cells store excess FAs as triglycerides (TGs). In cultured cells TG synthesis is activated by excess unsaturated but not saturated FAs. Here, we identify Ubxd8 as a sensor for unsaturated FAs and regulator of TG synthesis. In...
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Full title
Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis
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Record Identifier
TN_cdi_pubmed_primary_21115839
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21115839
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1011859107
