The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cy...
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
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United States
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English
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United States
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Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) require exposure to IL-23 to become encephalitogenic, but the mechanism by which IL-23 promotes their pathogenicity is not known. Here we found that IL-23 induced production of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) in T(H)17 cells and that GM-CSF had an...
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Full title
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
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TN_cdi_pubmed_primary_21516111
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21516111
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E-ISSN
1529-2916
DOI
10.1038/ni.2031
