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Pannexins in ischemia-induced neurodegeneration

Pannexins in ischemia-induced neurodegeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22147915

Pannexins in ischemia-induced neurodegeneration

About this item

Full title

Pannexins in ischemia-induced neurodegeneration

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20772-20777

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Pannexin 1 (Px1, Panx1) and pannexin 2 (Px2, Panx2) form large-pore nonselective channels in the plasma membrane of cells and were suggested to play a role in the pathophysiology of cerebral ischemia. To directly test a potential contribution of pannexins in ischemia-related mechanisms, we performed experiments in Px1–/–, Px2–/–, and Px1–/–Px2–/– k...

Alternative Titles

Full title

Pannexins in ischemia-induced neurodegeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_22147915

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22147915

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1018262108

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