Morphine activates neuroinflammation in a manner parallel to endotoxin
Morphine activates neuroinflammation in a manner parallel to endotoxin
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Opioids create a neuroinflammatory response within the CNS, compromising opioid-induced analgesia and contributing to various unwanted actions. How this occurs is unknown but has been assumed to be via classic opioid receptors. Herein, we provide direct evidence that morphine creates neuroinflammation via the activation of an innate immune receptor...
Alternative Titles
Full title
Morphine activates neuroinflammation in a manner parallel to endotoxin
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_22474354
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22474354
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1200130109
