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Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22991470

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

About this item

Full title

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

Author / Creator

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (40), p.16288-16293

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Mitochondrial dysfunctions cause numerous human disorders. A platform technology based on biodegradable polymers for carrying bioactive molecules to the mitochondrial matrix could be of enormous potential benefit in treating mitochondrial diseases. Here we report a rationally designed mitochondria-targeted polymeric nanoparticle (NP) system and its...

Alternative Titles

Full title

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_22991470

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22991470

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1210096109

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