Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenes...
Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
In vitro evidence suggests that plasmacytoid dendritic cells (pDCs) are intimately involved in the pathogenesis of lupus. However, it remains to be determined whether these cells are required in vivo for disease development, and whether their contribution is restricted to hyperproduction of type I IFNs. To address these issues, we created lupus-pre...
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Full title
Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus
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TN_cdi_pubmed_primary_23382217
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23382217
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1222798110
