Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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An increasing number of studies continue to show that the amyloid β (Aβ) peptide adopts an alternative conformation and acquires transmissibility; hence, it becomes a prion. Here, we report on the attributes of two strains of Aβ prions formed from synthetic Aβ peptides composed of either 40 or 42 residues. Modifying the conditions for Aβ polymeriza...
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Full title
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice
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TN_cdi_pubmed_primary_24982137
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_24982137
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1408968111
