Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase
Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Significance Antiinfectives, drugs that inhibit virulence strategies of microbial pathogens without affecting bacterial growth, may prevent hospital-acquired infections caused by antibiotic-resistant Staphylococcus aureus . We used virtual screening and synthetic optimization to identify 3,6-disubstituted triazolothiadiazole compounds as inhibitors...
Alternative Titles
Full title
Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_25197057
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25197057
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1408601111
