IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenti...
IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells
About this item
Full title
Author / Creator
Guenova, Emmanuella , Skabytska, Yuliya , Hoetzenecker, Wolfram , Weindl, Günther , Sauer, Karin , Tham, Manuela , Kim, Kyu-Won , Park, Ji-Hyeon , Seo, Ji Hae , Ignatova, Desislava , Cozzio, Antonio , Levesque, Mitchell P , Volz, Thomas , Köberle, Martin , Kaesler, Susanne , Thomas, Peter , Mailhammer, Reinhard , Ghoreschi, Kamran , Schäkel, Knut , Amarov, Boyko , Eichner, Martin , Schaller, Martin , Clark, Rachael A , Röcken, Martin and Biedermann, Tilo
Publisher
United States
Journal title
Language
English
Formats
Publication information
Publisher
United States
Subjects
More information
Scope and Contents
Contents
Interleukin 4 (IL-4) can suppress delayed-type hypersensitivity reactions (DTHRs), including organ-specific autoimmune diseases in mice and humans. Despite the broadly documented antiinflammatory effect of IL-4, the underlying mode of action remains incompletely understood, as IL-4 also promotes IL-12 production by dendritic cells (DCs) and IFN-γ-p...
Alternative Titles
Full title
IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells
Authors, Artists and Contributors
Author / Creator
Skabytska, Yuliya
Hoetzenecker, Wolfram
Weindl, Günther
Sauer, Karin
Tham, Manuela
Kim, Kyu-Won
Park, Ji-Hyeon
Seo, Ji Hae
Ignatova, Desislava
Cozzio, Antonio
Levesque, Mitchell P
Volz, Thomas
Köberle, Martin
Kaesler, Susanne
Thomas, Peter
Mailhammer, Reinhard
Ghoreschi, Kamran
Schäkel, Knut
Amarov, Boyko
Eichner, Martin
Schaller, Martin
Clark, Rachael A
Röcken, Martin
Biedermann, Tilo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_25646481
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25646481
Other Identifiers
E-ISSN
1091-6490
DOI
10.1073/pnas.1416922112
