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GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time

GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26130804

GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time

About this item

Full title

GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (29), p.E3920-E3929

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock but also a seasonal clock. This neural network of ∼10,000 circadian oscillators encodes season-dependent day-length changes through a largely unknown mechanism. We show that region-intrinsic changes in the SCN fine-tune the degree of network synchrony and reorgani...

Alternative Titles

Full title

GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_26130804

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26130804

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1421200112

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