ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-posi...
ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Scope and Contents
Contents
The stringent response is a survival mechanism used by bacteria to deal with stress. It is coordinated by the nucleotides guanosine tetraphosphate and pentaphosphate [(p)ppGpp], which interact with target proteins to promote bacterial survival. Although this response has been well characterized in proteobacteria, very little is known about the effe...
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Full title
ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria
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TN_cdi_pubmed_primary_26951678
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26951678
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1522179113