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Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression

Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27695003

Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression

About this item

Full title

Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression

Publisher

United States

Journal title

Nature immunology, 2016-12, Vol.17 (12), p.1459

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

CD4
effector T cells (T
cells) and regulatory T cells (T
cells) undergo metabolic reprogramming to support proliferation and immunological function. Although signaling via the lipid kinase PI(3)K (phosphatidylinositol-3-OH kinase), the serine-threonine kinase Akt and the metabolic checkpoint kinase complex mTORC1 induces both expression of...

Alternative Titles

Full title

Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_27695003

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27695003

Other Identifiers

E-ISSN

1529-2916

DOI

10.1038/ni.3577

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