Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression
Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression
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Publisher
United States
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Language
English
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Publisher
United States
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Contents
CD4
effector T cells (T
cells) and regulatory T cells (T
cells) undergo metabolic reprogramming to support proliferation and immunological function. Although signaling via the lipid kinase PI(3)K (phosphatidylinositol-3-OH kinase), the serine-threonine kinase Akt and the metabolic checkpoint kinase complex mTORC1 induces both expression of...
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Full title
Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression
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TN_cdi_pubmed_primary_27695003
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27695003
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E-ISSN
1529-2916
DOI
10.1038/ni.3577