Structural and dynamic insights into the role of conformational switching in the nuclease activity o...
Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity
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United States: American Institute of Physics, Inc
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English
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Publisher
United States: American Institute of Physics, Inc
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Contents
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins constitute a microbial, adaptive immune system countering invading nucleic acids. Cas2 is a universal Cas protein found in all types of CRISPR-Cas systems, and its role is implicated in new spacer acquisition into CRISPR loci. In subtype I-C CRI...
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Full title
Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity
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TN_cdi_pubmed_primary_28612041
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28612041
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ISSN
2329-7778
E-ISSN
2329-7778
DOI
10.1063/1.4984052
